Translational Technologies

Developing Biosensors for Efficacy & Safety Testing

   

 

 

 

 

 

 

 

 

 

 

 

 

 

Fluorescent protein biosensors are being developed to target clinically relevant protein pathways or mechanisms in order to report aberrant intracellular cell signaling events associated with disease pathologies. The aim is to allow early, mechanistic-based detection of different cellular toxicities, known as modes of action, for use in microplate assays and human microphysiology systems.

Senutovitch, N., et al., ExpBiol Med (Maywood), 2015.