Li, Xiang, PhD

Postdoctoral Associate , Liver MicroPhysiology Systems Program Team

Mark T. Miedel, PhD

xiangli@pitt.edu

Office: W904 BST
Phone: 412-383-9893
Fax:

Biosketch

 

PhD in Electrical engineering, West Virginia University

Human Microphysiology Systems for liver disease modeling: Exploring and developing layered glass/plastic chips with vascular and hepatic components which is also integrated with pH and oxygen sensor. The ultimate goal of this project is to culture human hepatocytes and all the supporting non-parenchymal cells (either primary or iPSCs-derived) on a bio-printed ECM layers to mimic the composition, structure and function of the native live.

  •  Xu, S., Li, X., LaPenna, K.B., Yokota, S.D., Huke, S. and He, P., 2017. New insights into shear stress-induced endothelial signalling and barrier function: cell-free fluid versus blood flow. Cardiovascular research, 113(5), p.508.

 

  • Xu, S.*, Li, X.*, Liu, Y. and He, P., 2016. Development and Characterization of In Vitro Microvessel Network and Quantitative Measurements of Endothelial [Ca2+] i and Nitric Oxide Production. JoVE (Journal of Visualized Experiments), (111), pp.e54014-e54014. * contributed equally

 

  • Li, X.*, Xu, S.*, He, P. and Liu, Y., 2015. In Vitro Recapitulation of Functional Microvessels for the Study of Endothelial Shear Response, Nitric Oxide and [Ca 2+] i. PloS one, 10(5), p.e0126797. * contributed equally

 

  • Liu, Y. and Li, X., 2013. Microfluidic and Lab-on-Chip Technologies for Biosensors. Biosensors Based on Nanomaterials and Nanodevices, pp.443-78.

 

  • Li, X., Mearns, S.M., Martins-Green, M. and Liu, Y., 2013. Procedure for the Development of Multi-depth Circular Cross-sectional Endothelialized Microchannels-on-a-chip. JoVE (Journal of Visualized Experiments), (80), pp.e50771-e50771.

 

  • Li, X., Wu, N., Rojanasakul, Y. and Liu, Y., 2013. Selective stamp bonding of PDMS microfluidic devices to polymer substrates for biological applications. Sensors and Actuators A: Physical, 193, pp.186-192.

 

  • Huang, Z.*, Li, X.*, Martins-Green, M. and Liu, Y., 2012. Microfabrication of cylindrical microfluidic channel networks for microvascular research. Biomedical microdevices, 14(5), pp.873-883. * contributed equally