Publications

Proteomic Screening and Lasso Regression Reveal Differential Signaling in Insulin and Insulin-like Growth Factor I (IGF1) Pathways; Cemal Erdem, Alison M. Nagle, Angelo J. Casa, Beate C. Litzenburger, Yu-fen Wang, D. Lansing Taylor, Adrian V. Lee, and Timothy R. Lezon; Molecular & Cellular Proteomics, 2016, pp.mcp-M115
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High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome; Delgado, E., M.M. Boisen, R. Laskey, R. Chen, C. Song, J. Sallit, Z.A. Yochum, C.L. Andersen, M.J. Sikora, J. Wagner, S. Safe, E. Elishaev, A. Lee, R.P. Edwards, P. Haluska, G. Tseng, M. Schurdak, and S. Oesterreich; Gynecology Oncology, 2016, 141: p. 348-356
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A human liver microphysiology platform for investigating physiology, drug safety, and disease models; Vernetti, L.A., N. Senutovitch, R. Boltz, R. DeBiasio, T. Ying Shun, A. Gough, and D.L. Taylor; Exp Biol Med (Maywood), 2016. 241(1): p. 101-14
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A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine; Stern, A.M., M.E. Schurdak, I. Bahar, J.M. Berg, and D.L. Taylor; Journal of Biomolecular Screening, 2016. 21(6): p. 521-534
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Pointwise Mutual Information Quantifies Intra-Tumor Heterogeneity in Tissue Sections Labeled with Multiple Fluorescent Biomarkers; Spagnolo, D.M., R. Gyanchandani, Y. Al-Kofahi, T. Lezon, A. Gough, D.E. Meyer, F. Ginty, B. Sarachan, J. Fine, A.V. Lee, D.L. Taylor, and S.C. Chennubhotla; Journal of Pathology Informatics, 2016. In press.
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The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models; Gough, A., L. Vernetti, L. Bergenthal, T.Y. Shun, and D.L. Taylor; Applied In Vitro Toxicology, 2016. 2(2): p. 103-117
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A metric and workflow for quality control in the analysis of heterogeneity in phenotypic profiles and screens; Gough, A., T.Y. Shun, D. Lansing Taylor, and M. Schurdak; Methods, 2016. 96: p. 12-26
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Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers; Gearhart, T.L., R.C. Montelaro, M.E. Schurdak, C.D. Pilcher, C.R. Rinaldo, T. Kodadek, Y. Park, K. Islam, R. Yurko, E.T. Marques, Jr., and D.S. Burke; J Immunol Methods, 2016. 435: p. 85-9
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Fluorescent protein biosensors applied to microphysiological systems; Senutovitch, N., L. Vernetti, R. Boltz, R. DeBiasio, A. Gough, and D.L. Taylor; Exp Biol Med (Maywood), 2015. 240: p. 795–808
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High-Content Analysis with Cellular and Tissue Systems Biology: a Bridge between Cancer Cell Biology and Tissue-Based Diagnostics; Gough, A., T. Lezon, J.R. Faeder, C. Chennubhotla, R.F. Murphy, R. Critchley-Thorne, and D.L. Taylor; in The molecular basis of cancer, J. Mendelsohn, et al., Editors. 2015, Saunders/Elsevier: Philadelphia, PA. p. 369-392.
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A high-content, multiplexed screen in human breast cancer cells identifies profilin-1 inducers with anti-migratory activities; Joy, M.E., L.L. Vollmer, K. Hulkower, A.M. Stern, C.K. Peterson, R.C. Boltz, P. Roy, and A. Vogt; PLoS One, 2014. 9(2): p. e88350
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Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery; Gough, A.H., N. Chen, T.Y. Shun, T.R. Lezon, R.C. Boltz, C.E. Reese, J. Wagner, L.A. Vernetti, J.R. Grandis, A.V. Lee, A.M. Stern, M.E. Schurdak, and D.L. Taylor; PLoS One, 2014. 9(7): p. e102678
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Large-scale generation of human iPSC-derived neural stem cells/early neural progenitor cells and their neuronal differentiation; D'Aiuto, L., Y. Zhi, D. Kumar Das, M.R. Wilcox, J.W. Johnson, L. McClain, M.L. MacDonald, R. Di Maio, M.E. Schurdak, P. Piazza, L. Viggiano, R. Sweet, P.R. Kinchington, A.G. Bhattacharjee, R. Yolken, and V.L. Nimgaonkar; Organogenesis, 2014. 10(4): p. 365-77
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