Nina Senutovitch, PhD

Postdoctoral Associate, Dept. of Computational and Systems Biology & Drug Discovery Institute

Nina Senutovitch, PhD

ninas@pitt.edu

Office: W908 BST
Phone: 412-624-1238
Fax:

 

 

PhD in Biological Sciences, Carnegie Mellon University

My scientific interests include the development of novel fluorescent-based protein biosensors to detect and quantify real-time changes in intracellular events, particularly in the context of bioengineered human microphysiological systems. Fluorescence-based biosensors are critical components of a novel human liver microphysiological system developed by our group to improve drug development and drug screening efforts as well as disease characterization by providing early toxicity information.

  1. Hutson M. Shane, Alexander Peter G., Allwardt Vanessa, Aronoff David M., Bruner-Tran Kaylon L., Cliffel David E., Davidson Jeffrey M., Gough Albert, Markov Dmitry A., McCawley Lisa J., McKenzie Jennifer R., McLean John A., Osteen Kevin G., Pensabene Virginia, Samson Philip C., Senutovitch Nina K., Sherrod Stacy D., Shotwell Matthew S., Taylor D. Lansing, Tetz Lauren M., Tuan Rocky S., Vernetti Lawrence A., and Wikswo John P. “Organs-on-Chips as Bridges for Predictive Toxicology (2016).” Appl In Vitro Tox. 2(2): 97-102.
  2. Vernetti LA*, Senutovitch N*, Boltz R, DeBiasio R, Shun TY, Gough A, Taylor DL.“A human liver microphysiology platform for investigating physiology, drug safety, and disease models (2016).” Exp Biol Med (Maywood). 241(1):101-14. *co-authorship
  3. Senutovitch N*, Vernetti L*, Boltz R, DeBiasio R, Gough A, Taylor DL. “Fluorescent protein biosensors applied to microphysiological systems (2015).” Exp Biol Med (Maywood). 240(6):795-808. *co-authorship
  4. Bale SS, Vernetti L, Senutovitch N, Jindal R, Hegde M, Gough A, McCarty WJ, Bakan A, Bhushan A, Shun TY, Golberg I, DeBiasio R, Usta OB, Taylor DL, Yarmush ML. “In vitro platforms for evaluating liver toxicity (2014).” Exp Biol Med (Maywood). 239(9):1180-91.
  5. Bhushan A, Senutovitch N, Bale SS, McCarty WJ, Hegde M, Jindal R, Golberg I, Berk Usta O, Yarmush ML, Vernetti L, Gough A, Bakan A, Shun TY, DeBiasio R, Lansing Taylor D. “Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans (2013).” Stem Cell Res Ther. 2013;4 Suppl 1:S16.